105當歸萃取物對脂多醣誘導小鼠巨噬細胞 RAW264.7之抗發炎反應
論文分類:
碩士論文
學號:
P0430006
姓名:
林芸妗
指導教授:
許惠貞
畢業日期:
2017-07-01
參考文獻:
冯懿挺, 陈绍瑗, 傅承新. (2006). GC-MS 分析 3種不同栽培方式的當歸揮髮油成分. 中國中藥雜誌, 31(5), 432-434.
田景祥. (2013). 當歸的有效成分及其藥理作用的研究進展. 工企醫刊, 26(4), 364-365.
邓永健, 郭志伟, 王萌. (2006). 當歸的化學成份及其藥理作用研究進展. 新疆中醫藥, 24(5), 109-113.宋道阳, 程敏霞, & 陈义. (2016). 當歸芍藥散治療黃褐斑的臨床觀察簡. 中華中醫藥雜誌(8), 3369-3370.
张金霞. (2014). 中藥當歸丙酮提取物抗菌活性及成分鑑定 [D]. 蘭州理工大學.
李东, 王芳. (2014). 中藥當歸提取方法優選. 產業與科技論壇(18), 68-69.
李红法, 郭松波, 满淑丽, 范亚亚, 王婷婷, 李霞, 高文远. (2015). 乙醇分級沉澱提取黃芪多醣及其理化性質和抗氧化活性研究. 中國中藥雜誌, 40(11), 2112-2116.
俞诗源, 孟茹, 李重阳, 袁静, 魏娉婷. (2015). 當歸多醣對麻黃素小鼠肝組織抗氧化酶活性和 NF-κB, TNF-α 表達的影響. 西北師範大學學報: 自然科學版, 51(1), 75-81.
范欢, 刘晶, 张育君, 黄圣. (2015). 超聲波導入中藥美白面膜治療炎症後色素沉著療效觀察. 中國美容醫學, 24(3), 64-67.
徐翊庭, 翁清松, 江彰吉, 林尚明, 高國定. (2003). 探討兩種中藥萃取物對抗菌活性與敷布材之表面特性影響評估. 華岡紡織期刊, 10(3), 362-371.
高小迪. (2014). 海拔梯度對當歸的生理生化指標及品質的影響 [D]. 甘肅中醫學院.
康军. (2005). 當歸化學成分及其藥理作用研究進展. 醫藥產業資訊, 2(23), 120-120.
張同吳, 林玨羽, 曾英傑. (2015). 當歸, 丹參萃取物對抑制癌細胞之影響. 花蓮區農業改良場研究彙報(33), 33-43.
蔣丙煌. (2008). 當歸食品加工技術之研究 (2/3).
梁佳玟, 賴怡君, 朱燕華. (2004). 中草藥對於促發炎細胞激素生成之影響. J Chin Med, 15(4), 293-304.
Bhullar, S. K., and Buttar, H. S. (2015). Nanofiber devices for the targeted-delivery of therapeutically active plant and herbal ingredients. Biomedical Reviews, 26, 37-42.
Chao, W.-W., Hong, Y.-H., Chen, M.-L., and Lin, B.-F. (2010). Inhibitory effects of Angelica sinensis ethyl acetate extract and major compounds on NF-κB trans-activation activity and LPS-induced inflammation. Journal of Ethnopharmacology, 129(2), 244-249.
Chao, W.-W., and Lin, B.-F. (2011). Bioactivities of major constituents isolated from Angelica sinensis (Danggui). Chinese medicine, 6(1), 29.
Günther, J., Petzl, W., Zerbe, H., Schuberth, H.-J., Koczan, D., Goetze, L., and Seyfert, H.-M. (2012). Lipopolysaccharide priming enhances expression of effectors of immune defence while decreasing expression of pro-inflammatory cytokines in mammary epithelia cells from cows. BMC genomics, 13(1), 17.
Gong, F., Niu, J., and Pei, X. (2016). Clinical effects of Angelica dahurica dressing on patients with I-II phase pressure sores. Die Pharmazie-An International Journal of Pharmaceutical Sciences, 71(11), 665-669.
Guo, K., Xu, S., Yin, P., Wang, W., Song, X., Liu, F., . . . Zoccarato, I. (2011). Active components of common traditional Chinese medicine decoctions have antioxidant functions. Journal of animal science, 89(10), 3107-3115.
Iranshahi, M., Askari, M., Sahebkar, A., & Adjipavlou-Litina, D. (2015). Evaluation of antioxidant, anti-inflammatory and lipoxygenase inhibitory activities of the prenylated coumarin umbelliprenin. DARU Journal of Pharmaceutical Sciences, 17(2), 99-103.
Lee, H. J., Lee, H., Kim, M. H., Choi, Y. Y., Ahn, K. S., Um, J.-Y., . . . Yang, W. M. (2017). Angelica dahurica ameliorates the inflammation of gingival tissue via regulation of pro-inflammatory mediators in experimental model for periodontitis. Journal of Ethnopharmacology, 205, 16-21.
Lee, J.-H., Kim, K.-S., Lee, Y.-C., Cho, C.-W., Kim, K., and Chung, Y. S. (2017). Anticancer composition containing herbal extract: Google Patents.
Lee, S., Shin, D.-S., Kim, J. S., Oh, K.-B., and Kang, S. S. (2003). Antibacterial coumarins from Angelica gigas roots. Archives of Pharmacal Research, 26(6), 449-452.
LIU, S.-f., ZHANG, Z.-h., SUN, G.-q., HU, Y.-d., CHEN, H.-s., and YANG, X.-h. (2013). Research on the Chinese Medicine Residue Instead of the Cotton Seed Hull in Planting Pleurotus ostreatus [J]. Northern Horticulture, 12, 052.
MacMicking, J., Xie, Q.-w., and Nathan, C. (1997). Nitric oxide and macrophage function. Annual review of immunology, 15(1), 323-350.
Markus, J., Wang, D., Kim, Y.-J., Ahn, S., Mathiyalagan, R., Wang, C., and Yang, D. C. (2017). Biosynthesis, characterization, and bioactivities evaluation of silver and gold nanoparticles mediated by the roots of Chinese herbal Angelica pubescens Maxim. Nanoscale research letters, 12(1), 46.
Pervin, M., Hasnat, M., Debnath, T., Park, S. R., Kim, D. H., and Lim, B. O. (2014). Antioxidant, Anti‐Inflammatory and Antiproliferative Activity of Angelica Dahurica Root Extracts. Journal of food biochemistry, 38(3), 281-292.
Prakash, B., Singh, P., Goni, R., Raina, A. K. P., and Dubey, N. (2015). Efficacy of Angelica archangelica essential oil, phenyl ethyl alcohol and α-terpineol against isolated molds from walnut and their antiaflatoxigenic and antioxidant activity. Journal of food science and technology, 52(4), 2220-2228.
Rietschel, E. T., and Brade, H. (1992). Bacterial endotoxins. Scientific american, 267(2), 54-61.
Rojas, A., Padron, J., Caveda, L., Palacios, M., and Moncada, S. (1993). Role of nitric oxide pathway in the protection against lethal endotoxemia afforded by low doses of lipopolysaccharide. Biochemical and biophysical research communications, 191(2), 441-446.
Saw, C. L., Wu, Q., Su, Z. Y., Wang, H., Yang, Y., Xu, X., . . . Kong, A. N. (2013). Effects of natural phytochemicals in Angelica sinensis (Danggui) on Nrf2-mediated gene expression of phase II drug metabolizing enzymes and anti-inflammation. Biopharm Drug Dispos, 34(6), 303-311. doi:10.1002/bdd.1846
Sowndhararajan, K., and Kim, S. (2017). Neuroprotective and Cognitive Enhancement Potentials of Angelica gigas Nakai Root: A Review. Scientia Pharmaceutica, 85(2), 21.
Su, Y.-W., Chiou, W.-F., Chao, S.-H., Lee, M.-H., Chen, C.-C., and Tsai, Y.-C. (2011). Ligustilide prevents LPS-induced iNOS expression in RAW 264.7 macrophages by preventing ROS production and down-regulating the MAPK, NF-κB and AP-1 signaling pathways. International immunopharmacology, 11(9), 1166-1172.
Tsai, N.-M., Lin, S.-Z., Lee, C.-C., Chen, S.-P., Su, H.-C., Chang, W.-L., and Harn, H.-J. (2005). The antitumor effects of Angelica sinensis on malignant brain tumors in vitro and in vivo. Clinical cancer research, 11(9), 3475-3484.
Tse, T. (2003). Use of common Chinese herbs in the treatment of psoriasis. Clinical and experimental dermatology, 28(5), 469-475.
Wang, G.-H., Chen, C.-Y., Tsai, T.-H., Chen, C.-K., Cheng, C.-Y., Huang, Y.-H., . . . Chung, Y.-C. (2017). Evaluation of tyrosinase inhibitory and antioxidant activities of Angelica dahurica root extracts for four different probiotic bacteria fermentations. Journal of Bioscience and Bioengineering, 123(6), 679-684.
Wang, K., Tang, Z., Wang, J., Cao, P., Li, Q., Shui, W., . . . Zhang, Y. (2017). Polysaccharide from Angelica sinensis ameliorates high-fat diet and STZ-induced hepatic oxidative stress and inflammation in diabetic mice by activating the Sirt1–AMPK pathway. The Journal of Nutritional Biochemistry, 43, 88-97.
Yan, Y.-h., Li, S.-h., Li, H.-y., Lin, Y., and Yang, J.-x. (2017). Osthole Protects Bone Marrow-Derived Neural Stem Cells from Oxidative Damage through PI3K/Akt-1 Pathway. Neurochemical research, 42(2), 398-405.
Yang, X., Zhao, Y., Wang, H., and Mei, Q. (2007). Macrophage activation by an acidic polysaccharide isolated from Angelica sinensis (Oliv.) Diels. Journal of biochemistry and molecular biology, 40(5), 636-643.
Zhang, S., He, B., Ge, J., Li, H., Luo, X., Zhang, H., . . . Liu, X. (2010). Extraction, chemical analysis of Angelica sinensis polysaccharides and antioxidant activity of the polysaccharides in ischemia–reperfusion rats. International journal of biological macromolecules, 47(4), 546-550.
Zhang, W.-f., Yang, Y., Li, X., Xu, D.-y., Yan, Y.-l., Gao, Q., . . . Duan, M.-h. (2017). Angelica polysaccharides inhibit the growth and promote the apoptosis of U251 glioma cells in vitro and in vivo. Phytomedicine.
Zhang, X.-d., Wu, Q., and Yang, S.-h. (2017). Ferulic acid promoting apoptosis in human osteosarcoma cell lines. Pakistan journal of medical sciences, 33(1), 127.
Zhang, X.-n., Ma, Z.-j., Wang, Y., Sun, B., Guo, X., Pan, C.-q., and Chen, L.-m. (2017). Angelica Dahurica ethanolic extract improves impaired wound healing by activating angiogenesis in diabetes. PLoS ONE, 12(5), e0177862.
Zhao, D., Islam, M. N., Ahn, B. R., Jung, H. A., Kim, B.-W., and Choi, J. S. (2012). In vitro antioxidant and anti-inflammatory activities of Angelica decursiva. Archives of Pharmacal Research, 35(1), 179-192.
Zhong, T., Zhang, H., Duan, X., Hu, J., Wang, L., Li, L., . . . Niu, L. (2017). Anti-obesity effect of radix Angelica sinensis and candidate causative genes in transcriptome analyses of adipose tissues in high-fat diet-induced mice. Gene, 599, 92-98.
Zhou, G.-F., Dai, X.-Y., Yu, C.-H., & Fang, J. (2013). Kinetic changes and antihypertensive effect of aqueous extract of Danggui (Angelica sinensis radix) after stir-fry processing. Food Science and Biotechnology, 22(3), 765-771.
田景祥. (2013). 當歸的有效成分及其藥理作用的研究進展. 工企醫刊, 26(4), 364-365.
邓永健, 郭志伟, 王萌. (2006). 當歸的化學成份及其藥理作用研究進展. 新疆中醫藥, 24(5), 109-113.宋道阳, 程敏霞, & 陈义. (2016). 當歸芍藥散治療黃褐斑的臨床觀察簡. 中華中醫藥雜誌(8), 3369-3370.
张金霞. (2014). 中藥當歸丙酮提取物抗菌活性及成分鑑定 [D]. 蘭州理工大學.
李东, 王芳. (2014). 中藥當歸提取方法優選. 產業與科技論壇(18), 68-69.
李红法, 郭松波, 满淑丽, 范亚亚, 王婷婷, 李霞, 高文远. (2015). 乙醇分級沉澱提取黃芪多醣及其理化性質和抗氧化活性研究. 中國中藥雜誌, 40(11), 2112-2116.
俞诗源, 孟茹, 李重阳, 袁静, 魏娉婷. (2015). 當歸多醣對麻黃素小鼠肝組織抗氧化酶活性和 NF-κB, TNF-α 表達的影響. 西北師範大學學報: 自然科學版, 51(1), 75-81.
范欢, 刘晶, 张育君, 黄圣. (2015). 超聲波導入中藥美白面膜治療炎症後色素沉著療效觀察. 中國美容醫學, 24(3), 64-67.
徐翊庭, 翁清松, 江彰吉, 林尚明, 高國定. (2003). 探討兩種中藥萃取物對抗菌活性與敷布材之表面特性影響評估. 華岡紡織期刊, 10(3), 362-371.
高小迪. (2014). 海拔梯度對當歸的生理生化指標及品質的影響 [D]. 甘肅中醫學院.
康军. (2005). 當歸化學成分及其藥理作用研究進展. 醫藥產業資訊, 2(23), 120-120.
張同吳, 林玨羽, 曾英傑. (2015). 當歸, 丹參萃取物對抑制癌細胞之影響. 花蓮區農業改良場研究彙報(33), 33-43.
蔣丙煌. (2008). 當歸食品加工技術之研究 (2/3).
梁佳玟, 賴怡君, 朱燕華. (2004). 中草藥對於促發炎細胞激素生成之影響. J Chin Med, 15(4), 293-304.
Bhullar, S. K., and Buttar, H. S. (2015). Nanofiber devices for the targeted-delivery of therapeutically active plant and herbal ingredients. Biomedical Reviews, 26, 37-42.
Chao, W.-W., Hong, Y.-H., Chen, M.-L., and Lin, B.-F. (2010). Inhibitory effects of Angelica sinensis ethyl acetate extract and major compounds on NF-κB trans-activation activity and LPS-induced inflammation. Journal of Ethnopharmacology, 129(2), 244-249.
Chao, W.-W., and Lin, B.-F. (2011). Bioactivities of major constituents isolated from Angelica sinensis (Danggui). Chinese medicine, 6(1), 29.
Günther, J., Petzl, W., Zerbe, H., Schuberth, H.-J., Koczan, D., Goetze, L., and Seyfert, H.-M. (2012). Lipopolysaccharide priming enhances expression of effectors of immune defence while decreasing expression of pro-inflammatory cytokines in mammary epithelia cells from cows. BMC genomics, 13(1), 17.
Gong, F., Niu, J., and Pei, X. (2016). Clinical effects of Angelica dahurica dressing on patients with I-II phase pressure sores. Die Pharmazie-An International Journal of Pharmaceutical Sciences, 71(11), 665-669.
Guo, K., Xu, S., Yin, P., Wang, W., Song, X., Liu, F., . . . Zoccarato, I. (2011). Active components of common traditional Chinese medicine decoctions have antioxidant functions. Journal of animal science, 89(10), 3107-3115.
Iranshahi, M., Askari, M., Sahebkar, A., & Adjipavlou-Litina, D. (2015). Evaluation of antioxidant, anti-inflammatory and lipoxygenase inhibitory activities of the prenylated coumarin umbelliprenin. DARU Journal of Pharmaceutical Sciences, 17(2), 99-103.
Lee, H. J., Lee, H., Kim, M. H., Choi, Y. Y., Ahn, K. S., Um, J.-Y., . . . Yang, W. M. (2017). Angelica dahurica ameliorates the inflammation of gingival tissue via regulation of pro-inflammatory mediators in experimental model for periodontitis. Journal of Ethnopharmacology, 205, 16-21.
Lee, J.-H., Kim, K.-S., Lee, Y.-C., Cho, C.-W., Kim, K., and Chung, Y. S. (2017). Anticancer composition containing herbal extract: Google Patents.
Lee, S., Shin, D.-S., Kim, J. S., Oh, K.-B., and Kang, S. S. (2003). Antibacterial coumarins from Angelica gigas roots. Archives of Pharmacal Research, 26(6), 449-452.
LIU, S.-f., ZHANG, Z.-h., SUN, G.-q., HU, Y.-d., CHEN, H.-s., and YANG, X.-h. (2013). Research on the Chinese Medicine Residue Instead of the Cotton Seed Hull in Planting Pleurotus ostreatus [J]. Northern Horticulture, 12, 052.
MacMicking, J., Xie, Q.-w., and Nathan, C. (1997). Nitric oxide and macrophage function. Annual review of immunology, 15(1), 323-350.
Markus, J., Wang, D., Kim, Y.-J., Ahn, S., Mathiyalagan, R., Wang, C., and Yang, D. C. (2017). Biosynthesis, characterization, and bioactivities evaluation of silver and gold nanoparticles mediated by the roots of Chinese herbal Angelica pubescens Maxim. Nanoscale research letters, 12(1), 46.
Pervin, M., Hasnat, M., Debnath, T., Park, S. R., Kim, D. H., and Lim, B. O. (2014). Antioxidant, Anti‐Inflammatory and Antiproliferative Activity of Angelica Dahurica Root Extracts. Journal of food biochemistry, 38(3), 281-292.
Prakash, B., Singh, P., Goni, R., Raina, A. K. P., and Dubey, N. (2015). Efficacy of Angelica archangelica essential oil, phenyl ethyl alcohol and α-terpineol against isolated molds from walnut and their antiaflatoxigenic and antioxidant activity. Journal of food science and technology, 52(4), 2220-2228.
Rietschel, E. T., and Brade, H. (1992). Bacterial endotoxins. Scientific american, 267(2), 54-61.
Rojas, A., Padron, J., Caveda, L., Palacios, M., and Moncada, S. (1993). Role of nitric oxide pathway in the protection against lethal endotoxemia afforded by low doses of lipopolysaccharide. Biochemical and biophysical research communications, 191(2), 441-446.
Saw, C. L., Wu, Q., Su, Z. Y., Wang, H., Yang, Y., Xu, X., . . . Kong, A. N. (2013). Effects of natural phytochemicals in Angelica sinensis (Danggui) on Nrf2-mediated gene expression of phase II drug metabolizing enzymes and anti-inflammation. Biopharm Drug Dispos, 34(6), 303-311. doi:10.1002/bdd.1846
Sowndhararajan, K., and Kim, S. (2017). Neuroprotective and Cognitive Enhancement Potentials of Angelica gigas Nakai Root: A Review. Scientia Pharmaceutica, 85(2), 21.
Su, Y.-W., Chiou, W.-F., Chao, S.-H., Lee, M.-H., Chen, C.-C., and Tsai, Y.-C. (2011). Ligustilide prevents LPS-induced iNOS expression in RAW 264.7 macrophages by preventing ROS production and down-regulating the MAPK, NF-κB and AP-1 signaling pathways. International immunopharmacology, 11(9), 1166-1172.
Tsai, N.-M., Lin, S.-Z., Lee, C.-C., Chen, S.-P., Su, H.-C., Chang, W.-L., and Harn, H.-J. (2005). The antitumor effects of Angelica sinensis on malignant brain tumors in vitro and in vivo. Clinical cancer research, 11(9), 3475-3484.
Tse, T. (2003). Use of common Chinese herbs in the treatment of psoriasis. Clinical and experimental dermatology, 28(5), 469-475.
Wang, G.-H., Chen, C.-Y., Tsai, T.-H., Chen, C.-K., Cheng, C.-Y., Huang, Y.-H., . . . Chung, Y.-C. (2017). Evaluation of tyrosinase inhibitory and antioxidant activities of Angelica dahurica root extracts for four different probiotic bacteria fermentations. Journal of Bioscience and Bioengineering, 123(6), 679-684.
Wang, K., Tang, Z., Wang, J., Cao, P., Li, Q., Shui, W., . . . Zhang, Y. (2017). Polysaccharide from Angelica sinensis ameliorates high-fat diet and STZ-induced hepatic oxidative stress and inflammation in diabetic mice by activating the Sirt1–AMPK pathway. The Journal of Nutritional Biochemistry, 43, 88-97.
Yan, Y.-h., Li, S.-h., Li, H.-y., Lin, Y., and Yang, J.-x. (2017). Osthole Protects Bone Marrow-Derived Neural Stem Cells from Oxidative Damage through PI3K/Akt-1 Pathway. Neurochemical research, 42(2), 398-405.
Yang, X., Zhao, Y., Wang, H., and Mei, Q. (2007). Macrophage activation by an acidic polysaccharide isolated from Angelica sinensis (Oliv.) Diels. Journal of biochemistry and molecular biology, 40(5), 636-643.
Zhang, S., He, B., Ge, J., Li, H., Luo, X., Zhang, H., . . . Liu, X. (2010). Extraction, chemical analysis of Angelica sinensis polysaccharides and antioxidant activity of the polysaccharides in ischemia–reperfusion rats. International journal of biological macromolecules, 47(4), 546-550.
Zhang, W.-f., Yang, Y., Li, X., Xu, D.-y., Yan, Y.-l., Gao, Q., . . . Duan, M.-h. (2017). Angelica polysaccharides inhibit the growth and promote the apoptosis of U251 glioma cells in vitro and in vivo. Phytomedicine.
Zhang, X.-d., Wu, Q., and Yang, S.-h. (2017). Ferulic acid promoting apoptosis in human osteosarcoma cell lines. Pakistan journal of medical sciences, 33(1), 127.
Zhang, X.-n., Ma, Z.-j., Wang, Y., Sun, B., Guo, X., Pan, C.-q., and Chen, L.-m. (2017). Angelica Dahurica ethanolic extract improves impaired wound healing by activating angiogenesis in diabetes. PLoS ONE, 12(5), e0177862.
Zhao, D., Islam, M. N., Ahn, B. R., Jung, H. A., Kim, B.-W., and Choi, J. S. (2012). In vitro antioxidant and anti-inflammatory activities of Angelica decursiva. Archives of Pharmacal Research, 35(1), 179-192.
Zhong, T., Zhang, H., Duan, X., Hu, J., Wang, L., Li, L., . . . Niu, L. (2017). Anti-obesity effect of radix Angelica sinensis and candidate causative genes in transcriptome analyses of adipose tissues in high-fat diet-induced mice. Gene, 599, 92-98.
Zhou, G.-F., Dai, X.-Y., Yu, C.-H., & Fang, J. (2013). Kinetic changes and antihypertensive effect of aqueous extract of Danggui (Angelica sinensis radix) after stir-fry processing. Food Science and Biotechnology, 22(3), 765-771.
